Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000282) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-PfMATE MaL6
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| Synonyms |
Macrocyclic peptide MaL6
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| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Selection Method | Random non-standard peptide integrated discovery system | |||||
| Highest Status | Research | |||||
| PDB ID | 3WBN | |||||
| Sequence Length | 17 | |||||
| SBP Sequence |
>Macrocyclic peptide anti-PfMATE MaL6
Acf-TFRYSPSLYTWFLFPC |
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| Sequence Description | Acf represents N-chloroacetyl-D-phenylalanine; Acf and Cys form a bridge. | |||||
| 3D Structure | ||||||
| Experimentally Validated Structure | ||||||
| Click to Save PDB File | ||||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
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| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Pyrococcus furiosus multidrug and toxic compound extrusion | Inhibitor | Tools as cocrystallization ligands of selenomethionine-labeled PfMATE | N.A. | The University of Tokyo | [1] | |