Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000277) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-SiRT2 S2iD7
|
|||||
| Synonyms |
Macrocyclic peptide S2iD7
|
|||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Expression System | FIT system | |||||
| Selection Method | mRNA display | |||||
| Highest Status | Research | |||||
| Sequence Length | 14 | |||||
| SBP Sequence |
>Macrocyclic peptide anti-SiRT2 S2iD7
DYHDYRIK[Tfa]RYHTYPC |
|||||
| Sequence Description | Tfa represents epsilon-N-trifluoroacetyl group; Ac and Cys form a bridge. | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| NAD-dependent protein deacetylase sirtuin-2 | Inhibitor | Research tool | Kd: 3.7 nM | The University of Tokyo | [1] | |