Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000274) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
Macrocyclic peptide anti-E6AP CM11-3
|
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| Synonyms |
Macrocyclic peptide CM11-3
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| Molecular Weight | 1.8 kDa | |||||
| Design Method | de novo protein design | |||||
| Expression System | FIT system | |||||
| Selection Method | mRNA display | |||||
| Highest Status | Research | |||||
| Sequence Length | 14 | |||||
| SBP Sequence |
>Macrocyclic peptide anti-E6AP CM11-3
[d-Trp]CDV[MeS]HY[MeF]PY[MeF]PCG |
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| Sequence Description | Ac and Cys form a bridge; [MeS] represents N-methylserine; [MeF] represents N-methylphenylalanine; [MeG] represents N-methylglycine. | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS044 | [1] | ||||
| Scaffold Name | Macrocyclic peptide | |||||
| Scaffold Class | Non-Antibody | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| Ubiquitin-protein ligase E3A | Binder | Human papillomaviruse infection(HPV16) | Kd: 1.2 nM | The University of Tokyo | [1] | |