General Information of Synthetic Binding Protein (SBP) (ID: SBP000163)
SBP Name
DART anti-Beta-diketone/CD3 DART
Synonyms
h38C2 x v9 DART
Molecular Weight 50 kDa
Design Method Traditional methods (Site-directed mutagenesis and/or Directed evolution)
Highest Status Research
Protein Scaffold Information of This SBP
Scaffold ID PS028
Scaffold Info
[1]
Scaffold Name DART
Scaffold Class Antibody fragment
Fold Type Beta-Sheets + Loops
Binding Target(s) of This SBP (BTS)
BTS Name Details Mechanism Application Affinity Research Organization Ref
T-cell surface glycoprotein CD3
BTS Info
Binder Ovarian cancer [ICD-11: 2C73.Z] N.A. National Institutes of Health [1]
Beta-diketone
BTS Info
Binder Ovarian cancer [ICD-11: 2C73.Z] N.A. National Institutes of Health [1]
References
1 Chemically Programmed Bispecific Antibodies in Diabody Format. J Biol Chem. 2016 Sep 9;291(37):19661-73.