Details of the SBP
| General Information of Synthetic Binding Protein (SBP) (ID: SBP000162) | ||||||
|---|---|---|---|---|---|---|
| SBP Name |
DART anti-FOLR1/CD3 DART
|
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| Synonyms |
FOLR1 x CD3 DART
|
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| Molecular Weight | 50 kDa | |||||
| Design Method | Traditional methods (Site-directed mutagenesis and/or Directed evolution) | |||||
| Highest Status | Research | |||||
| Protein Scaffold Information of This SBP | ||||||
|---|---|---|---|---|---|---|
| Scaffold ID | PS028 | [1] | ||||
| Scaffold Name | DART | |||||
| Scaffold Class | Antibody fragment | |||||
| Fold Type | Beta-Sheets + Loops | |||||
| Binding Target(s) of This SBP (BTS) |
|---|
| BTS Name | Details | Mechanism | Application | Affinity | Research Organization | Ref |
|---|---|---|---|---|---|---|
| T-cell surface glycoprotein CD3 | Binder | Ovarian cancer [ICD-11: 2C73.Z] | N.A. | National Institutes of Health | [1] | |
| Folate receptor alpha | Binder | Ovarian cancer [ICD-11: 2C73.Z] | N.A. | National Institutes of Health | [1] | |