General Information of Binding Target of SBP (BTS) (ID: ST00424)
BTS Name
Digoxin
Synonyms
Digoxin
BTS Type
Small Molecule
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Fab anti-Digoxin D10 Research Binder Kd: 0.5 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D11 Research Binder Kd: 0.2 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D24 Research Binder Kd: 0.5 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D25 Research Binder Kd: 0.5 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D32 Research Binder Kd: 18.6 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D34 Research Binder Kd: 0.7 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D36 Research Binder Kd: 22 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D37 Research Binder Kd: 0.7 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D38 Research Binder Kd: 2.3 nM Research tool
SBP Info
[1]
Fab anti-Digoxin D4-1 Research Binder Kd: 3.4 nM Research tool
SBP Info
[2]
Fab anti-Digoxin D4-2 Research Binder Kd: 5.7 nM Research tool
SBP Info
[2]
Fab anti-Digoxin D4-3 Research Binder Kd: 0.006 nM Research tool
SBP Info
[2]
Fab anti-Digoxin D4-4 Research Binder Kd: 0.9 nM Research tool
SBP Info
[2]
Fab anti-Digoxin D4-5 Research Binder Kd: 3.5 nM Research tool
SBP Info
[2]
Fab anti-Digoxin D4-6 Research Binder Kd: 1.8 nM Research tool
SBP Info
[2]
Fab anti-Digoxin F6-1 Research Binder Kd: 3.9 nM Research tool
SBP Info
[2]
Fab anti-Digoxin F6-2 Research Binder Kd: 5.6 nM Research tool
SBP Info
[2]
Fab anti-Digoxin G6-1 Research Binder Kd: 4.3 nM Research tool
SBP Info
[2]
Fab anti-Digoxin G6-2 Research Binder Kd: 0.3 nM Research tool
SBP Info
[2]
References
1 A single H:CDR3 residue in the anti-digoxin antibody 26-10 modulates specificity for C16-substituted digoxin analogs. Protein Eng. 2001 Apr;14(4):287-96.
2 Contribution of antibody heavy chain CDR1 to digoxin binding analyzed by random mutagenesis of phage-displayed Fab 26-10. J Biol Chem. 1995 Dec 1;270(48):28541-50.