General Information of Binding Target of SBP (BTS) (ID: ST00401)
BTS Name
Human immunoglobulin E Receptor Fc-epsilon-RIa
Synonyms
IgE Receptor Fc-epsilon-RIa
BTS Type
Protein
Organism
Homo sapiens (Human)
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
DARPin anti-Fc-epsilon-RIa clone B-A4-85 Research Antagonist Kd: 3.9 nM Allergies [ICD-11: 4A84.Z]
SBP Info
[1]
DARPin anti-Fc-epsilon-RIa clone C-A3-30 Research Antagonist Kd: 2.1 nM Allergies [ICD-11: 4A84.Z]
SBP Info
[1]
References
1 Current Strategies to Inhibit High Affinity FcRI-Mediated Signaling for the Treatment of Allergic Disease. Front Immunol. 2019 Feb 7;10:175.