General Information of Binding Target of SBP (BTS) (ID: ST00326)
BTS Name
BCII_beta_lactamase
BTS Type
Protein
Family
Metallo-beta-lactamase superfamily;
Class-B beta-lactamase family
Organism
uncultured bacterium
UniProt ID
A0A059X2Z2
UniProt Entry
A0A059X2Z2_9BACT
PFam
PF00753
Sequence
MKTLLILCISLLSWASALAQSPTIQVSKLEENFYVHTSYNTYQGQLVPSNGMIVNTPKGV
ILIDTAWGDEQTQQLLAWIKKELRRKVILVIVTHAHSDRMGGIRTITKEKIRIVSTPFIR
ERAGQINENYGEYRPEPALSSDTTLTFGSLKTRVFYPGKGHAPENVVVWFPAQKILFGGC
FIKSVASTNLGNLSDADIPEWKLSLHRTEEKFPKPNIVIPGHGDPGGPELLTRTRELLDI
GK
Sequence Length
242
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Nanobody anti-BCII_beta_lactamase cAbBCII10-0-0-0 Research Binder Kd: 17 nM Research tool
SBP Info
[1]
Nanobody anti-BCII_beta_lactamase cAbBCII10-0-0-1 Research Binder Kd: 14 nM Research tool
SBP Info
[1]
Nanobody anti-BCII_beta_lactamase cAbBCII10-0-1-0 Research Binder Kd: 15 nM Research tool
SBP Info
[1]
Nanobody anti-BCII_beta_lactamase cAbBCII10-0-1-1 Research Binder Kd: 12 nM Research tool
SBP Info
[1]
Nanobody anti-BCII_beta_lactamase cAbBCII10-1-0-0 Research Binder Kd: 4.3 nM Research tool
SBP Info
[1]
Nanobody anti-BCII_beta_lactamase cAbBCII10-1-0-1 Research Binder Kd: 11 nM Research tool
SBP Info
[1]
Nanobody anti-BCII_beta_lactamase cAbBCII10-1-1-0 Research Binder Kd: 5.5 nM Research tool
SBP Info
[1]
Nanobody anti-BCII_beta_lactamase cAbBCII10-1-1-1 Research Binder Kd: 16 nM Research tool
SBP Info
[1]
References
1 Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains. J Mol Biol. 2008 Mar 21;377(2):478-88.