General Information of Binding Target of SBP (BTS) (ID: ST00299)
BTS Name
Ferritin
BTS Type
Protein
Family
Ferritin family
Organism
Homo sapiens (Human)
Function
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
UniProt ID
Q8TD27
UniProt Entry
Q8TD27_HUMAN
PFam
PF00210
Sequence
MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLEFPS
PISPSPSCWHHYTTNRPQPQHHLLRPRRRKRPHSIPTPILIFRSP
Sequence Length
165
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
TEM1-beta-lactamase based binder anti-Ferritin clone 503-1 Research Binder Kd: 20 nM Research tool
SBP Info
[1]
TEM1-beta-lactamase based binder anti-Ferritin clone 503-3 Research Binder Kd: 10 nM Research tool
SBP Info
[1]
References
1 TEM-1 beta-lactamase as a scaffold for protein recognition and assay. Protein Sci. 2002 Jun;11(6):1506-18.