General Information of Binding Target of SBP (BTS) (ID: ST00284)
BTS Name
Streptavidin
BTS Type
Protein
Family
Avidin/streptavidin family
Organism
Streptomyces avidinii
Function
The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
UniProt ID
P22629
UniProt Entry
SAV_STRAV
PFam
PF01382
Sequence
MRKIVVAAIAVSLTTVSITASASADPSKDSKAQVSAAEAGITGTWYNQLGSTFIVTAGAD
GALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQY
VGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPSAASIDAAKKAGVNNGNPLDA
VQQ
Sequence Length
183
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
scFv anti-SV M-STR1 Research Binder Kd: 6.3 nM Research tool
SBP Info
[1]
scFv anti-SV P-STR3 Research Binder Kd: 2.2 nM Research tool
SBP Info
[1]
TEM1-beta-lactamase based binder anti-SV SVL1-01 Research Binder Kd: 100 nM Research tool
SBP Info
[2]
TEM1-beta-lactamase based binder anti-SV SVL3-02 Research Binder Kd: 460 nM Research tool
SBP Info
[2]
References
1 Two ScFv antibody libraries derived from identical VL-VH framework with different binding site designs display distinct binding profiles. Protein Eng Des Sel. 2013 Oct;26(10):683-93.
2 TEM-1 beta-lactamase as a scaffold for protein recognition and assay. Protein Sci. 2002 Jun;11(6):1506-18.