Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00272) | ||||||
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| BTS Name |
Nucleoprotein
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| Synonyms |
Nucleocapsid protein; NC; Protein N
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| BTS Type |
Protein
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| Family |
Gammacoronavirus nucleocapsid protein family
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| Gene Name |
N
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| Organism |
Avian infectious bronchitis virus (strain M41) (IBV)
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| Function |
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Sequence |
MASGKATGKTDAPAPVIKLGGPKPPKVGSSGNASWFQAIKANKLNIPPPKFEGSGVPDNE
NLKSSQQHGYWRRQATFKPGKGGRKPVPDAWYFYYTGTGPAANLNWGDSQDGIVWVAGKG ADTKFRSNQGTRDSDKFDQYPLRFSDGGPDGNFRWDFIPLNGGRSGRSTAASSAASSRAP SREVSRGRRSGSEDDLIARAARIIQDQQKKGSRITKAKADEMAHRRYCKRTIPPNYKVDQ VFGPRTKGKEGNFGDDKMNEEGIKDGRVTAMLNLVPSSHACLFGSRVTPKLQPDGLHLKF EFTTVVPRDDPQFDNYVKICDQCVDGVGTRPKDDEPRPKSRSSSRPATRGNSPAPRQQRP KKEKKPKKHDDEVDKALTSDEERNNAQLEFYDEPKVINWGDAALGENEL |
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| Sequence Length |
409
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| scFv anti-IBV ZL.256 | Research | Binder | N.A. | Infectious bronchitis virus infection(IBV infection) | [1] | |
| scFv anti-IBV ZL.78 | Research | Binder | N.A. | Infectious bronchitis virus infection(IBV infection) | [1] | |