Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00248) | ||||||
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| BTS Name |
Cyclin-dependent kinase 1
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| Synonyms |
CDK1; EC 2.7.11.22; EC 2.7.11.23; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase
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| BTS Type |
Protein
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| Family |
Protein kinase superfamily;
CMGC Ser/Thr protein kinase family; CDC2/CDKX subfamily |
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| Gene Name |
Cdk1
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| Organism |
Drosophila melanogaster (Fruit fly)
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| Function |
Plays a key role in the control of the eukaryotic cell cycle It is required in higher cells for entry into S-phase and mitosis In embryos, promotes the release of Rif1 from chromatin during mid-blastula transition p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Gene ID | ||||||
| Sequence |
MEDFEKIEKIGEGTYGVVYKGRNRLTGQIVAMKKIRLESDDEGVPSTAIREISLLKELKH
ENIVCLEDVLMEENRIYLIFEFLSMDLKKYMDSLPVDKHMESELVRSYLYQITSAILFCH RRRVLHRDLKPQNLLIDKSGLIKVADFGLGRSFGIPVRIYTHEIVTLWYRAPEVLLGSPR YSCPVDIWSIGCIFAEMATRKPLFQGDSEIDQLFRMFRILKTPTEDIWPGVTSLPDYKNT FPCWSTNQLTNQLKNLDANGIDLIQKMLIYDPVHRISAKDILEHPYFNGFQSGLVRN |
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| Sequence Length |
297
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Peptide aptamer anti-CDK1 Pep8 | Research | Inhibitor | N.A. | Eye Defects | [1] | |