General Information of Binding Target of SBP (BTS) (ID: ST00239)
BTS Name
Casein kinase II subunit beta
Synonyms
CK II beta; Phosvitin; Protein G5a
BTS Type
Protein
Family
Casein kinase 2 subunit beta family
Gene Name
CSNK2B
Organism
Homo sapiens (Human)
Function
Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine Participates in Wnt signaling (By similarity).
UniProt ID
P67870
UniProt Entry
CSK2B_HUMAN
PFam
PF01214
Gene ID
1460
Sequence
MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDE
ELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPML
PIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPA
NQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
Sequence Length
215
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Peptide aptamer anti-CKII-beta P1 Research Binder Kd: 400 nM Tools for protein function modulation
SBP Info
[1]
References
1 Peptide aptamers with biological and therapeutic applications. Curr Med Chem. 2011;18(27):4215-22.