Details of the BTS
| General Information of Binding Target of SBP (BTS) (ID: ST00211) | ||||||
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| BTS Name |
Cys-loop ligand-gated ion channel
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| Synonyms |
ELIC
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| BTS Type |
Protein
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| Family |
Ligand-gated ion channel (TC 1.A.9) family
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| Organism |
Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi)
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| Function |
Mediates cation-selective currents but does not discriminate between different monovalent cations.
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| UniProt ID | ||||||
| UniProt Entry | ||||||
| PFam | ||||||
| Sequence |
APADNAADARPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVEN
TQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFP FDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRKASTHISDIRYDHLSSV QPNQNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWLESFSERLQTSFTLMLT VVAYAFYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHHRQAMGVEDDLLIQRCR LAFPLGFLAIGCVLVIRGITL |
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| Sequence Length |
321
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| Synthetic Binding Protein (SBP) Targeting This BTS |
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| SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
|---|---|---|---|---|---|---|
| Nanobody anti-ELIC clone 21 | Research | Modulator | N.A. | Research tool | [1] | |
| Nanobody anti-ELIC clone 22 | Research | Binder | N.A. | Research tool | [1] | |
| Nanobody anti-ELIC clone 72 | Research | Modulator | N.A. | Research tool | [2] | |