Details of the BTS
General Information of Binding Target of SBP (BTS) (ID: ST00184) | ||||||
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BTS Name |
Tumor necrosis factor receptor superfamily member 18
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Synonyms |
Glucocorticoid-induced TNFR-related protein; CD antigen CD357
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BTS Type |
Protein
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Gene Name |
Tnfrsf18
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Organism |
Mus musculus (Mouse)
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Function |
Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity).
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UniProt ID | ||||||
UniProt Entry | ||||||
Gene ID | ||||||
Sequence |
MGAWAMLYGVSMLCVLDLGQPSVVEEPGCGPGKVQNGSGNNTRCCSLYAPGKEDCPKERC
ICVTPEYHCGDPQCKICKHYPCQPGQRVESQGDIVFGFRCVACAMGTFSAGRDGHCRLWT NCSQFGFLTMFPGNKTHNAVCIPEPLPTEQYGHLTVIFLVMAACIFFLTTVQLGLHIWQL RRQHMCPRETQPFAEVQLSAEDACSFQFPEEERGEQTEEKCHLGGRWP |
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Sequence Length |
228
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Synthetic Binding Protein (SBP) Targeting This BTS |
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SBP Name | Highest Status | Mechanism | Affinity | Application | Details | Ref |
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Human VH dAb anti-GITR VHB82(SS)-6 | Research | Binder | Kd: 196 nM | Research tool | [1] | |