General Information of Binding Target of SBP (BTS) (ID: ST00039)
BTS Name
CD27 antigen
Synonyms
CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD antigen CD27
BTS Type
Protein
Gene Name
CD27
Organism
Homo sapiens (Human)
Function
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
UniProt ID
P26842
UniProt Entry
CD27_HUMAN
PFam
PF00020
Gene ID
939
Sequence
MARPHPWWLCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAA
QCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTEC
DPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPP
QRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCHYSCPREE
EGSTIPIQEDYRKPEPACSP
Sequence Length
260
Synthetic Binding Protein (SBP) Targeting This BTS
SBP Name Highest Status Mechanism Affinity Application Details Ref
Affimer anti-CD27 AVA-014 Research Agonist N.A. Cancers [ICD-11: 2D4Z]
SBP Info
[1]
References
1 Avacta. Product Development Pipeline. 2021.